Guyton\Walker lives and works in New York. Solo exhibitions include Kunsthaus Bregenz, Austria (2013); Baltimore Museum of Art (2010); Greene Naftali, New York (2009, 2005); Museo d’Arte Moderna di Bologna (2008); and the Carpenter Center for the Visual Arts, Harvard University, Cambridge, Massachusetts (2006). Their work has been included in significant group shows at the Museum Brandhorst, Munich (2015); The Renaissance Society, University of Chicago (2014); Guggenheim Bilbao (2011); The Museum of Modern Art, New York (2010); and the 53rd Venice Biennale (2009).

Guyton\Walker is held in the collections of the Albright-Knox Art Gallery, Buffalo; Astrup Fearnley Museet, Oslo; Baltimore Museum of Art; Centre Georges Pompidou, Paris; The Museum of Contemporary Art, Chicago; and The Museum of Modern Art, New York.